I'm a doctor, had my career derailed by severe depression

by omgredditgotme

I'm a doctor, had my career derailed by severe depression. Was taught through medical school that anything that's an MAOI is spooky scary, only for people who would kill themselves otherwise b/c life on them was barely worth living. I started questioning this after I read through some of Dr. Gillman's papers, and having a strong background in neurophysiology it became obvious that the fear of MAOIs at this point is more religious than scientific. As luck would have it, my psychiatrist had started using MAOIs on patients after being frustrated with poor response to literally everything else.

Been on TCP [tranylcypromine] for 14 days now, it's like someone turned the the switch to my brain back on. There's color in the world again… Pain in parts of my body I thought would just be there until I died, gone. Side effects are so laughable as to barely deserve mentioning…

https://www.reddit.com/r/MAOIs/comments/t502ou/in_theory_i_knew_but_wow/

In remission

by Curious-Tourist-2432

I achieved remission from Parnate.

The anhedonia was the closest thing I can imagine to being actual hell. Every day was a blurry, brain numbing nightmare that never seemed to end.

The Parnate took a while to see any actual changes. After I’d gone through my first box of 10x10’s, I’d just about given up on it doing anything, but I still had that sliver of hope…

It wasn’t until 2 weeks or so ago, on 80mg, that I woke up one day in full remission. I walked down the hall and realised I felt lighter. I put my earphones in and turned on my music to test it. As I did, I noticed the colours on the album covers were vibrant again. I looked up and everything was more vivid, it was like my eyes changed definition. Then I pressed play to that delicious sound of music, with the biggest grin on my face, and danced for hours…

Ever since I introduced L-Tryophan about a week ago, I have not had a day with anhedonia since. I am now 100% in remission and can enjoy every single thing that I didn’t before…

I’m so grateful for this amazing second chance at life I’ve been given. I will not take anything for granted ever again. I hope that through this post I’ve given at least one person hope. You are all warriors. You will get out of this. I promise. You just have to know that even if you can’t see the light at the end of the tunnel right now, it’s there. You will be free from this curse. And you will escape this darkness.

https://www.reddit.com/r/anhedonia/comments/1587r0o/in_remission/

Cured my anhedonia with Nardil!

by chewingbuttons

I can’t believe it. I’ve been off work for a while now and after taking Nardil I’ve been socialising way more, applying for jobs, got my lust back for life, feeling more motivated and happy. Honestly PLEASE PLEASE try MAOI’s if you haven’t yet and have tried everything else. Feel like a new person!

https://www.reddit.com/r/anhedonia/comments/12vxd5l/cured_my_anhedonia_with_nardil/

A happy story of overcoming anhedonia

by shivering_asf

Past, in 2018, I was in a terrible state of anhedonia, to the point I resorted to everything…

I went to lot of psychiatrists, and they put me on almost every kind of antidepressant around, and I waited the 6-8 weeks, and saw no change, some of them even worsened the thing. So, on early 2019, I went to a psychiatrist known and respected for trying novel approaches on mental illness. After a long talk (about 2:30h) he put me on buprenorphine patches 20mg, amissulpride 50mg (now lowered to 25mg), Vyvanse 50mg, and Stablon 12.5mg 3 times a day…

After 2 weeks, my old self started to emerge, I started crying at every feeling I had, because was so new and intense… But there was a thing that really got me again: music, when in heard Hallelujah, the Jeff Buckley version (in was a great fan of him, but music stopped touching me) I went to tears, his history of life touched me with me the lyrics, I went to an ecstatic state, that reminded me of my MDMA and LSD experiences. From that moment on, I felt cured.

Sorry for the long post, or typos, I am from Brazil. Good luck for you all, and remember: there's hope, you may be broken, but somewhere into you, your old self is awaiting to be awakened.

https://www.reddit.com/r/anhedonia/comments/joymxe/a_happy_story_of_overcoming_anhedonia/

How long on parnate did it take for your anhedonia to go away?

wch7601: About 4-5 months as I ramped up tp 70mg a day, then tapered down to 60mg a day. It really relieved the anhedonia...now I can laugh, appreciate beauty, not take myself so seriously. I've actually been able to terminate psychotherapy for now! Stay with it...

https://www.reddit.com/r/MAOIs/comments/ko133v/how_long_of_parnate_did_it_take_for_your/

Parnate Empathy

by toilet_poster

I have experienced complete relief of depression, OCD, and nearly complete relief of ADHD on parnate. But that's not what I want to talk about, it's the empathy. When I was a teenager I wondered if I was a sociopath (edgy, I know, but bear with me), because I just felt nothing for other people. Of course, I was actually depressed.

On parnate, I've become the complete opposite. I am thinking about how other people are feeling, remembering things they've said to inform that, reading their reactions, and overall now have an incredibly good sense of what's really going on in other people's heads. Furthermore, I use that information to try to help people, because I really, really want to. I want them to be as happy as I am now. Not only am I more personable and engaging, but I'm also kind and thoughtful.

https://www.reddit.com/r/MAOIs/comments/u4ccex/parnate_empathy/

Parnate gave me back a full range of emotion and the ability to appreciate more things more deeply. No more feeling numb or detached or listless or meaningless.

https://www.reddit.com/r/MAOIs/comments/14zmgre/comment/jstke9q/

Success story after 7 months on Parnate

by guicookie

Hey folks,

It's been a while since I've checked in here.

I remember how valuable it was to read other people's success stories with MAOIs when I was learning about them, then adjusting to them.

At that time I had zero hope. It was literally two years since I had laughed.

I've been on Parnate 50mg (30mg AM, 20mg Lunch) for seven-ish months now. My cognition, sleep, range of feeling, engagement and enjoyment of life are as close to 100% as they've ever been.

New job, better family life, better all round. I'm laughing again.

It took me seven-ish weeks from starting Parnate to finding my effective dose of 50mg. From that point I've had significant, sustained improvement.

I am very grateful to this community and I wish you all the best, wherever you're at.

https://www.reddit.com/r/MAOIs/comments/wmnn0y/success_story_after_7_months_on_parnate/